MHF TOP PICKS FOR OCTOBER
Every month, we at the Mueller Health Foundation like to showcase interesting news and updates in the field of tuberculosis. Below are our top 3 picks for October:
- Global Burden of Disease Due to Rifampicin-Resistant Tuberculosis: A Mathematical Modeling Analysis
In 2020, almost half a million individuals developed rifampicin-resistant tuberculosis (RR-TB). In this study, the researchers estimated the global burden of RR-TB over the lifetime of affected individuals. They synthesized data on incidence, case detection, and treatment outcomes in 192 countries. Using a mathematical model, they projected disability-adjusted life years (DALYs) over the lifetime for individuals developing tuberculosis in 2020 stratified by country, age, sex, HIV, and rifampicin resistance. The research concluded that the incidence of RR-TB in 2020 was responsible for an estimated 6.9 million DALYs, 44% of which accrued among TB survivors. While the South-East Asia Region was estimated to have the greatest absolute burden of RR-TB, former Soviet Union countries and southern African countries had the highest burden of RR-TB per population. To learn more, you can access the full article at: https://www.nature.com/articles/s41467-023-41937-9
- Programmatic Implementation of Depression Screening and Remote Mental Health Support Sessions for Persons Recently Diagnosed with TB in Lima, Peru
An international study on the outskirts of Lima in Peru assessed the impact of
providing comprehensive mental health care on depression and tuberculosis
treatment outcomes. The research team found that nearly half of those starting
treatment for tuberculosis exhibited depressive symptoms. By providing a
combination of mental health and social service programs depressive symptoms
not only improved, but also correlated with better treatment outcomes. Programs
included psychoeducation, mutual support groups, occupational therapy and
urgent referrals for higher-level mental health care. Looking ahead, these
community-rooted strategies that are centered on patients and creating equitable,
long-term partnerships with local leaders and health systems, are some of the
most powerful methods for transforming and strengthening health systems and
improving access to care, particularly for people with low incomes and members of
marginalized populations. To learn more, you can read the paper here:
https://www.researchgate.net/publication/370634076_Programmatic_ implementation_of_depression_screening_and_remote_mental_health_ support_sessions_for_persons_recently_diagnosed_with_TB_in_Lima_Peru_ during_the_COVID-19_pandemic
DID YOU KNOW?
We would like to highlight some of the outstanding work that our grantee REACH in India has been doing as part of creating a novel community-care model for people with drug-resistant tuberculosis in the Chennai area. Below are a few highlights that showcase significant improvements accomplished with the implementation of the pilot communitycare model in 2023:
- REACH hosts survivor meetings for patients that have been diagnosed with DR-TB to share their experiences with each other. These meetings also help to close the feedback loop for practitioners on how to best support patients in their journey of battling DR-TB. The REACH coodinators also incorporate family members and friends of the patients into these meetings to provide a learning opportunity on how to best support patients undergoing treatment.
- REACH collaborated with students at the local university to create and perform a puppet show to educate the local communities about basic information related to DR-TB. The puppet show also highlighted the importance of seeking treatment to prevent spread.
- The REACH team has also created flyers in English as well as multiple local languages to help communities better understand basic facts about DR-TB, including the importance of testing for the disease and adhering to the treatment.
- The REACH team also compiled a comprehensive landscape review of community-care models in India and around the world to help structure and best define a set of patient-centered services needed in the novel community-care model for DR-TB that is being piloted in the Chennai region of India this year.
- A baseline comparison to 2022 DR-TB detection and treatment of patients already showed great effectiveness of the novel community-care model for DR-TB. Compared to not having an intervention in 2022, implementing the DR-TB community-care model already increased the diagnosis of DR-TB patients by approximately 115% in the Chennai region.
- Additionally, in 2022 without any intervention, approximately 81% of people diagnosed with TB received treatment, compared to 94% of people diagnosed with TB who were put on treatment with the implementation of the new communitycare model in the first half of 2023.
- Without any interventions, only 59% of patients receiving treatment continued or completed the treatment course in 2022. With the new community-care model, within the first half of the year, 100% of patient stayed on the recommended treatment regimen and there was no loss to follow-up or death.