Summary of Impact 2020
The Mueller Health Foundation
Investments Made
530,000 USD Distributed in Grant Funds in 2020
4,016,000 USD Committed through 2024
Investments Made by Strategic Pillar
$ 470,000 USD
$ 30,000 USD
$ 30,000 USD
Partnerships
Publications
8
New Partnerships
Established
2
Press Releases
1
Scientific Paper
Publication
Education
1
Educational Video to
Increase Awareness for
TB
1
Infographic
Comparing TB and
COVID 19
Communication
2,900%
Increase in Twitter
Followers
3,800%
Increase in LinkedIn
Followers
>100
Average Views per Post on LinkedIn and Twitter
TBConnect Blockchain Application Platform Initiative
1
Application Development Roadmap
1
Complete Set of Specifications and User Stories
>25
Wireframes Created
3
Add-on features including blockchain smart-contracts capability, messaging, and teleconferencing
3
Phases of Application Development Completed
1
Iterative Testing Strategy and Developed and >120 Bugs Fixed
Our Partners
InveniAI TBMeld AI-Platform Initiative
1. TB Prevention: Identification of Targets to Increase BCG Vaccine Efficacy
18
Scientific Research Databases and Gene Databases scanned
195,588
Scientific papers queried for identification of targets which can be combined with the TB BCG Vaccine to increase its efficacy
98
Targets identified for potential combination with BCG to enhance efficacy of the BCG vaccine
66 Human
Targets
32 M.tb Targets
75
Shortlisted targets ranked for Biological and Clinical relevance
12
Top targets selected for Pathway-based Analysis
2. TB Treatment: Discovery of Novel and Alternative Treatment Combinations
18
Scientific Research Databases and Gene Databases scanned
192,513
Scientific papers queried for identification of targets which can be combined with the TB BCG Vaccine to increase its efficacy
364
Relevant immune targets and pathways identified that can be further analyzed as new/alternative targets treatment combinations
231 Human Targets
133 M.tb
Targets
14
Top targets selected for Synergy Assessment through Framework-based analysis
Boston Children’s Hospital Precision Vaccine Program
3
New Hires, including 1 media relations expert and 2 laboratory members
1
Planned, created, and convened working group of experts in vaccinology, immunology and infectious diseases to conduct landscape analysis of existing BCG vaccines
Optimized antigen-specific in vitro readouts that will be used with fluorophore-conjugated Ag85b
Optimized flow cytometry panel to observe in vivo Th1/Th2/Th17 polarization
100
BCG Denmark (SS I) vials sourced and en-route
+
20
BCG India vials in-house
1
Identified and evaluated participation in phase 2 clinical trial to assess G-Japan BCG in its ability to prevent viral respiratory infections, such as COVID-19
1
Movie script for a 7-minute video to educate high-school students and above on tuberculosis
19
Television interviews conducted by Ofer Levy, PhD